The role of island-arc oceanic, collisional and intraplate magmatism in the formation of continental crust in the Mongolia-Trasnbaikalia region: geostructural, geochronological and Sm-Nd isotope data

The formation of continental crust in the Mongolia-Transbaikalia region is researched to identify the mechanisms of interactions between the crust and the mantle in the development of the Neoarchean, Proterozoic and Paleozoic magmatic and sedimentary complexes in the study area.Using the results of his own studies conducted for many years and other

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Anti-fibrotic activity of a rho-kinase inhibitor restores outflow function and intraocular pressure homeostasis

Glucocorticoids are widely used as an ophthalmic medication.A common, sight-threatening adverse event of glucocorticoid usage is ocular hypertension, caused by dysfunction of the conventional outflow pathway.We report that netarsudil, a rho-kinase inhibitor, decreased glucocorticoid-induced ocular hypertension in patients whose intraocular pressure

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An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS.

Genetic mutations of FUS have been linked to many diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration.A Hockey Skates - Junior - Performance primate specific and polymorphic retrotransposon of the SINE-VNTR-Alu (SVA) family is present upstream of the FUS gene.Here we have demonstrated that this retrotranspos

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